What is the significance of GABA in relation to anxiety?

GABA, or gamma-aminobutyric acid, is an inhibitory neurotransmitter that plays a crucial role in reducing neuronal excitability throughout the nervous system. Its significance in relation to anxiety primarily stems from its function in promoting calmness and relaxation. In the context of anxiety disorders, lower levels of GABA are often associated with heightened levels of anxiety because GABA helps to inhibit excessive neural activity. When GABA levels are optimal, they contribute to a sense of tranquility, thereby reducing the symptoms of anxiety. Thus, GABA's link to anxiety disorders is established through its regulation of neuronal activity, emphasizing the importance of its role in managing anxiety levels.