How is depression generally characterized?

Depression is generally characterized by a persistent low mood, pervasive feelings of sadness, and significant guilt. Individuals experiencing depression often report a loss of interest or pleasure in activities they once enjoyed, along with symptoms such as fatigue, difficulty concentrating, and changes in sleep or appetite. The feelings of sadness can be overwhelming and can lead to a sense of hopelessness. Guilt may stem from a negative perception of oneself or feelings of worthlessness, which are common in depression. This depiction aligns with the clinical understanding of major depressive disorder as outlined in diagnostic manuals, reinforcing that the correct option accurately reflects the core symptoms associated with the condition.